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Biotech Production Technician

Company Overview

Vyriad is a clinical stage biotechnology company focused on curing cancer using potent, safe and cost effective cancer therapies utilizing engineered replication competent viruses designed to selectively and rapidly destroy cancer. Revolutionizing cancer treatment is our long-term goal, requiring curiosity, perseverance, an openness to challenging convention and a commitment to excellence. The challenges are complex, the work pace is fast, and progress is seldom a straight line. All of this makes for an exhilarating environment of collaboration, discovery and fun.

Position Overview

The Biotech Production Technician will be responsible for manufacturing of oncolytic viruses and other biologics for clinical trials, as well as preclinical process development. The Biotech Production Technician plays a vital role in the day-to-day manufacturing operations in compliance with cGMP standards. Bioproduction involves aseptic processing in a pharmaceutical cleanroom facility, large-scale cell culture, vector generation, purification, concentration, and fill and finish operations, according to established standard operating procedures (SOPs). In addition, staff are responsible for the daily operations and environmental monitoring of the GMP facility to ensure compliance with applicable regulations.

Principal Duties & Responsibilities

  • Performs all aspects of cGMP manufacturing of clinical grade viruses and viral vectors following established SOPs.
  • Performs preclinical grade viral vector production, scale-up and process development.
  • Reviews, edits, completes and revises batch records, worksheets and SOPs in accordance with Good Document practices.
  • Prepares reagents and ensures inventory for the manufacture of clinical and preclinical viral vectors.
  • Performs set up, dismantling, and maintenance of equipment and ensures equipment is ready for production operations.
  • Performs manufacturing level maintenance on equipment.
  • Participates in equipment installation, commissioning and validation.
  • Maintains manufacturing equipment and records.
  • Participates in quality control testing of clinical and preclinical grade vectors.
  • Assists with facility cleaning, changeover, and staging of materials.
  • Collaborates closely with the process development, Quality Control and Quality Assurance teams.

Other Responsibilities

  • Practices and promotes safe work habits and adheres to safety procedures and guidelines.
  • Provide technical representation during internal and external audits.
  • Keeps up to date with current technologies and trends in drug product processing.
  • Perform routine tasks including general housekeeping, equipment monitoring and maintenance.

Education, Training & Experience

  • Life sciences degree (Bachelors) in Scientific, Engineering or Healthcare subject area. Experience with upstream and/or downstream manufacture and testing of biologics under cGMP compliance is high desirable.
  • Prior laboratory experience in research and/or analytical technique desirable.
  • Viral vector production experience highly desirable.
  • Ability to apply scientific principles utilized to solve operational, as well as routine production tasks.
  • Excellent documentation skills including comprehension, review and establishing Batch Production Records, SOPs, deviations and summary reports.

Job Type:



Monday-Friday 8:00 – 5:00


Rochester, MN (Required)

Work authorization:

Work visa sponsorship is not available for this position.

Compensation and benefits:

Salary is commensurate with experience and qualifications. A comprehensive benefits package including:

  • Paid Holidays
  • PTO
  • Employer paid Short- and Long-Term Disability
  • Life Insurance
  • AD&D
  • Dental Insurance
  • Simple IRA with an employer match

How to apply

To apply please send a resume and cover letter to References will be requested and background checks will be required prior to start of employment. Applications will be reviewed as received until the position is filled.

Please note this job description is not designed to cover or contain a comprehensive listing of activities, duties or responsibilities that are required of the employee for this job. Duties, responsibilities and activities may change at any time with or without notice.

Vyriad is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, gender, gender identity, national origin, genetics, disability, age, sexual orientation or veteran status.

Apply today

To apply, please send your resume and cover letter to

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